Ampulla Cardiomyopathy (Takotsubo Cardiomyopathy)-- - A Review
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چکیده
Transient left ventricular apical ballooning also known as Takotsubo cadiomyopathy or "broken heart syndrome" has been described by investigators worldwide. There have been several cases reported in Japan's journals between 1990 and 2001. It was first described by Sato et al and Dote et al and was named "Takotsubo" -shaped cardomyopathy due to its unique "short neck round-flask" -like LV apical ballooning resembling the tako-tsubo (Japanese for octopus pot or trap) of Japan. In recent years, a lot of patients with clinical presentation resembling acute myocardial infarction, such as chest pain, electrocardiography(EKG) abnormalities and elevated cardiac markers, have been found to have normal coronary arteries during the procedure of coronary angiography. The syndrome is characterized by transient left ventricular apical wall motion abnormality with hyper-or-normalcontraction of the basal region resulting in characteristic "ballooning" of the apex of the left ventricle. Besides, the transient regional systolic dysfunction also involves the right ventricle and recently, a new variant of transient LV ballooning, Abstract
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Takotsubo (ampulla) cardiomyopathy is characterized by slight to moderate elevation of cardiac enzymes. It is reasonable to think that the elevated levels are evidence of myocardial damage (cardiac-specific enzymes are released from the cytoplasm of damaged cardiac myocytes into extracellular fluid). Thus, it is problematic to consider takotsubo cardiomyopathy as (neurogenic) stunned myocardium...
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. Hurst RT, Prasad A, Askew JW 3rd, Sengupta PP, Tajik AJ. Takotsubo cardiomyopathy: a unique cardiomyopathy with variable ventricular morphology. J Am Coll Cardiol Img 2010;3:641–9. . Donohue D, Ahsan C, Sanaei-Ardekani M, Movahed MR. Early diagnosis of stress-induced apical ballooning syndrome based on classic echocardiographic findings and correlation with cardiac catheterization. J Am Soc E...
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